CD8+/DR+ T gamma cells inhibit the autologous mixed lymphocyte reaction
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چکیده
منابع مشابه
Autologous rosette-forming T cells as the responding cells in human autologous mixed-lymphocyte reaction.
Autologous rosette-forming cells (Tar cells) have surface and functional characteristics of post-thymic precursors and among these characteristics there are some that have been identified in the responsive cell of the autologous mixed-lymphocyte reaction (AMLR). We therefore did AMLR with circulating mononuclear cells from normal subjects using as responding cells either total T cells, T cells ...
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Isolated human T4+ cells proliferate in the autologous mixed lymphocyte reaction (AMLR), whereas isolated T8+ cells do not. However, in the presence of Interleukin 2 or T4+ cells, the T8+ cells demonstrated substantial proliferation. These studies suggest that T8+ cells recognize signals from autologous non-T cells, but require an additional factor for the subsequent proliferative response. Sin...
متن کاملThe autologous mixed lymphocyte reaction and dendritic cells.
levede M. Relevance of urinary excretion of alcian blue-glycosaminoglycans complexes and hydroxyproline to disease activity in rheumatoid arthritis. J Rheumatol 1982;9: 579-83. 16. Chuck AJ, Murphy J, Weiss JB, Greenan DM. Comparison of urinary glycosaminoglycan excretion in rheumatoid arthritis, osteoarthritis, myocardial infarction, and controls. Ann Rheum Dis 1986;45:162-6. 17. Moss DW. Alka...
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The autologous mixed lymphocyte reaction (auto-MLR) measures the ability of non-T cells to stimulate autologous T cells to proliferate in tissue culture. The auto-MLR was studied in 1 1 patients with autoimmune thrombocytopenic purpura (ATP). Seven patients had decreased auto-MLR. which averaged 4440 ± 3364 cpm (SEM) compared to 1 5.360 ± 6905 cpm for simultaneously studied controls. The averag...
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In autologous mixed lymphocyte reaction (MLR), T cells proliferate in response to the stimulation by autologous non-T cells. In the present study, human T cell subpopulations, defined by murine monoclonal antibodies OKT4, OKT8, or 9.3, were examined for their capacity to proliferate in autologous and allogeneic MLR. It was observed that the treatment of responder T cells with OKT4 or 9.3 antibo...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2008
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.1990.tb05423.x